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Anti-thyroid peroxidase (TPO) antibodies support the autoimmune etiology of Hashimoto's disease, though thyroid ultrasound is not routinely indicated unless nodules or goiter are present

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Early signs of response include reduced appetite, smaller portion satisfaction, and declining fasting blood glucose or HbA1c in those with diabetes

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The timing of Semaglutide administration can influence side effects for some individuals

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