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In accord with the upregulated expression of all the ThDP-dependent dehydrogenases, transcripts of the thiamine/ThDP transporters and the major producer of ThDP from thiamine, i.e., thiamine diphosphokinase (TPK), as well as probable ThMP phosphatase ACP1, also undergo a long-term upregulation (Figure 4B)

the mucosal immune system, plays a key role in food allergies (176)

335 Astrocytes in post-mortem samples of patients with mesial temporal lobe epilepsy show significant down-regulation of K ir 4.1 channels critical for K + buffering

Pediatr Nephrol 30:13491360

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This is not a failure of the medication