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Animals were anesthetized intramuscularly with a ketaminexylazine mixture composed of 30 mg/kg ketamine and 12 mg/kg xylazine, respectively, with a total injection volume of 1.2 mL/kg

These medications work by reducing hunger, slowing stomach emptying, and altering food preferences, which can lead to lower calorie intake and, in some cases, unintended side effects such as nausea, constipation, and loss of lean muscle mass

J Pharmacol Pharmacother (2013) 4(3):17686.10.4103/0976-500X.114596 6 NasrallahHAMeyerJMGoffDCMcEvoyJPDavisSMStroupTSet alLow rates of treatment for hypertension, dyslipidemia and diabetes in schizophrenia: data from the CATIE schizophrenia trial sample at baseline

Consult a medical doctor before starting any diet or exercise program or if you have any known or suspected medical condition(s) and/or if you are taking any prescription or medication(s)

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