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Unrealistic goals can lead to frustration and disappointment
It is a tightly regulated reaction that depends on both the availability of the amino acids (cysteine, glycine, and glutamate) and the rate-limiting enzyme, glutamate-cysteine ligase ( GCL )
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Vekic J, Stromsnes K, Mazzalai S, Zeljkovic A, Rizzo M, Gambini J
Reduced bloating, better digestion, less inflammation in the gut lining
The in vivo HITI-mediated knock-in efficiency at the Alb locus in this study is comparable to that of other knock-in methods, such as HDR (~2%) and NHEJ (~2%) 33,34
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