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A.FosterJ
In more marked situations (particularly in children with rare metabolic disorders), episodes of hypoglycaemia during fasting may also be observed
The reduced caloric intake, combined with metabolic adaptation, can produce feelings of low energy during the first several weeks at each new dose level
The absence of formal data does not mean absence of risk
Importantly, suspected adverse reactions to any medicine including unlicensed, counterfeit, or unregulated products can and should be reported to the MHRA via the Yellow Card Scheme at yellowcard.mhra.gov.uk or through the Yellow Card app
In our experience, this is the single most common reconstitution error: researchers assume shaking speeds dissolution and improves mixing, when in reality it destroys the product entirely
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