When side effects do occur, they are typically very mild and temporary
Choline supplementation of the mothers of unborn rats, as well as rat pups during the first month of life, leads to improved performance in spatial memory tests months after choline supplementation has been discontinued (123)
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doi:10.1021/jf402866q Rollini M, Manzoni M (2006) Influence of different fermentation parameters on glutathione volumetric productivity by Saccharomyces cerevisiae
8,9 Table 1 Risk Factors for Vitamin B12 Deficiency A multicenter randomized controlled trial of 390 patients with diabetes mellitus showed that those taking 850 mg of metformin three times per day had an increased risk of vitamin B 12 deficiency (number needed to harm = 14 per 4.3 years) and low vitamin B 12 levels (number needed to harm = 9 per 4.3 years) vs
