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Trials of synthetic GnRH analogs and insulin signaling modulators describe diminished hyperandrogenism and more regular cycles in subsets of PCOS women

Both target similar health goals but work through different mechanisms and currently have very different availability statuses

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They have dedicated review teams that can engage in sponsor consultations to clarify requirements

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so what this study suggests is that when hormone therapy is clinically indicated and you combine it with GLP one therapy, that may yield an additive or synergistic effect on weight loss