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Stomach acid is necessary to release vitamin B12 from food, and intrinsic factor is required for its absorption

10.1111/j.1365-2125.2012.04172.x 3 DrmicD.KolencD.IlicS.BaukL.SeverM.Zenko SeverA.et al (2017)

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The peptide activates extracellular signal-regulated kinase 1/2 (ERK1/2) phosphorylation in a dose-dependent manner, leading to nuclear translocation and activation of transcription factors including c-Fos, c-Jun, and early growth response-1 (Egr-1) that drive expression of genes involved in cell growth, migration, and angiogenesis

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