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References: Acton EK, et al

What to expect in your first month on Mounjaro During your first month on Mounjaro, youll likely experience several changes as your body adjusts to the medication: Week 1-2: Initial impact on appetite usually begin within 24-48 hours of your first injection You may notice reduced hunger and food cravings Youll likely feel fuller quicker Side effects like nausea or fatigue may appear (more on managing these below) Week 3-4: Weight loss typically becomes noticeable (2-4% of starting weight) Some people experience the medications effects wearing off 4-5 days after injection Hunger levels become more consistent Side effects generally start to decrease The SURMOUNT-1 trial data 1 shows that while the average weight loss is 2-4% in the first month, the range varies considerably

Verify your refrigerator maintains 28C, use proper aseptic technique during reconstitution, and track your administration window within a 60-minute range daily

1 But that doesnt account for the many others that didnt make the cut

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[Accessed 26/01/2026] Loperamide (Imodium)