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The FDA raised concerns about limited human trials, inconsistent chemical information, possible immune reactions and difficulty confirming the purity of finished products
Despite extensive investment in MASH drug development, only one medication (resmetirom) has been officially approved for MASH treatment to date
It may accelerate tissue-repair, affect bone-related signaling pathways, and improve metabolism in research models
Metformin for Weight Loss FAQs Can Metformin cause diarrhea
[8] [9] Lean muscle mass loss : Significant weight reduction may include loss of lean tissue, which could have implications for long-term metabolic health and physical function, particularly in older adults
