[1] A common starting regimen in adults with normal renal and hepatic function is 1 mL intramuscularly once or twice weekly, titrated every four weeks according to biochemical markers such as fasting lipid panel, liver transaminases, and serum carnitine
Typical starting range: Total weekly dosage may range from 4 to 8 mg, divided into 2-3 weekly administrations
Timing, morning upon waking
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Key Preclinical Study (Neelakantan et al., 2018): Treatment in diet-induced obese mice produced progressive body weight loss, reduced white adipose tissue mass and adipocyte size, decreased total cholesterol, and no changes in food intake effects were metabolic, not appetite-driven